Alternate processing of Flt1 transcripts is directed by conserved cis-elements within an intronic region of FLT1 that reciprocally regulates splicing and polyadenylation

The vascular endothelial growth factor receptor, Flt1 is a transmembrane receptor co-expressed with an alternate transcript encoding a secreted form, sFlt1, that functions as a competitive inhibitor of Flt1. Despite shared transcription start sites and upstream regulatory elements, sFlt1 is in far g...

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Detalles Bibliográficos
Autores principales: Thomas, Christie P., Raikwar, Nandita S., Kelley, Elizabeth A., Liu, Kang Z.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926593/
https://www.ncbi.nlm.nih.gov/pubmed/20385595
http://dx.doi.org/10.1093/nar/gkq198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926593/
https://www.ncbi.nlm.nih.gov/pubmed/20385595
http://dx.doi.org/10.1093/nar/gkq198

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