Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites

Transcription of protein-coding genes in trypanosomes is polycistronic and gene expression is primarily regulated by post-transcriptional mechanisms. Sequence motifs in the untranslated regions regulate mRNA trans-splicing and RNA stability, yet where UTRs begin and end is known for very few genes....

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Detalles Bibliográficos
Autores principales: Siegel, Tim Nicolai, Hekstra, Doeke R., Wang, Xuning, Dewell, Scott, Cross, George A. M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926603/
https://www.ncbi.nlm.nih.gov/pubmed/20385579
http://dx.doi.org/10.1093/nar/gkq237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926603/
https://www.ncbi.nlm.nih.gov/pubmed/20385579
http://dx.doi.org/10.1093/nar/gkq237

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