Functional selection and systematic analysis of intronic splicing elements identify active sequence motifs and associated splicing factors

Despite the critical role of pre-mRNA splicing in generating proteomic diversity and regulating gene expression, the sequence composition and function of intronic splicing regulatory elements (ISREs) have not been well elucidated. Here, we employed a high-throughput in vivo Screening PLatform for In...

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Detalles Bibliográficos
Autores principales: Culler, Stephanie J., Hoff, Kevin G., Voelker, Rodger B., Berglund, J. Andrew, Smolke, Christina D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926609/
https://www.ncbi.nlm.nih.gov/pubmed/20385591
http://dx.doi.org/10.1093/nar/gkq248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926609/
https://www.ncbi.nlm.nih.gov/pubmed/20385591
http://dx.doi.org/10.1093/nar/gkq248

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