Helix–hairpin–helix protein MJ1434 from Methanocaldococcus jannaschii and EndoIV homologue TTC0482 from Thermus thermophilus HB27 do not process DNA uracil residues

The mutagenic threat of hydrolytic DNA cytosine deamination is met mostly by uracil DNA glycosylases (UDG) initiating base excision repair. However, several sequenced genomes of archaeal organisms are devoid of genes coding for homologues of the otherwise ubiquitous UDG superfamily of proteins. Prev...

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Detalles Bibliográficos
Autores principales: Schomacher, Lars, Smolorz, Sabine, Ciirdaeva, Elena, Ber, Svetlana, Kramer, Wilfried, Fritz, Hans-Joachim
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926615/
https://www.ncbi.nlm.nih.gov/pubmed/20410075
http://dx.doi.org/10.1093/nar/gkq270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926615/
https://www.ncbi.nlm.nih.gov/pubmed/20410075
http://dx.doi.org/10.1093/nar/gkq270

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