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Sequence-specific recognition of methylated DNA by human zinc-finger proteins

DNA methylation is an essential epigenetic mark. Three classes of mammalian proteins recognize methylated DNA: MBD proteins, SRA proteins and the zinc-finger proteins Kaiso, ZBTB4 and ZBTB38. The last three proteins can bind either methylated DNA or unmethylated consensus sequences; how this is achi...

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Detalles Bibliográficos
Autores principales: Sasai, Nobuhiro, Nakao, Mitsuyoshi, Defossez, Pierre-Antoine
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926618/
https://www.ncbi.nlm.nih.gov/pubmed/20403812
http://dx.doi.org/10.1093/nar/gkq280