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Identifying compositionally homogeneous and nonhomogeneous domains within the human genome using a novel segmentation algorithm

It has been suggested that the mammalian genome is composed mainly of long compositionally homogeneous domains. Such domains are frequently identified using recursive segmentation algorithms based on the Jensen–Shannon divergence. However, a common difficulty with such methods is deciding when to ha...

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Detalles Bibliográficos
Autores principales: Elhaik, Eran, Graur, Dan, Josić, Krešimir, Landan, Giddy
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926622/
https://www.ncbi.nlm.nih.gov/pubmed/20571085
http://dx.doi.org/10.1093/nar/gkq532