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Tumor-Stromal Interactions Influence Radiation Sensitivity in Epithelial- versus Mesenchymal-Like Prostate Cancer Cells

HS-27a human bone stromal cells, in 2D or 3D coultures, induced cellular plasticity in human prostate cancer ARCaP(E) and ARCaP(M) cells in an EMT model. Cocultured ARCaP(E) or ARCaP(M) cells with HS-27a, developed increased colony forming capacity and growth advantage, with ARCaP(E) exhibiting the...

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Detalles Bibliográficos
Autores principales: Josson, Sajni, Sharp, Starlette, Sung, Shian-Ying, Johnstone, Peter A. S., Aneja, Ritu, Wang, Ruoxiang, Gururajan, Murali, Turner, Timothy, Chung, Leland W. K., Yates, Clayton
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926670/
https://www.ncbi.nlm.nih.gov/pubmed/20798867
http://dx.doi.org/10.1155/2010/232831