Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis

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We present a computational method, TuMult, for reconstructing the sequence of copy number changes driving carcinogenesis, based on the analysis of several tumor samples from the same patient. We demonstrate the reliability of the method with simulated data, and describe applications to three differe...

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Detalles Bibliográficos
Autores principales: Letouzé, Eric, Allory, Yves, Bollet, Marc A, Radvanyi, François, Guyon, Frédéric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926787/
https://www.ncbi.nlm.nih.gov/pubmed/20649963
http://dx.doi.org/10.1186/gb-2010-11-7-r76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926787/
https://www.ncbi.nlm.nih.gov/pubmed/20649963
http://dx.doi.org/10.1186/gb-2010-11-7-r76

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