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Lentivirus-mediated RNA interference of vascular endothelial growth factor in monkey eyes with iris neovascularization

PURPOSE: To explore the in vivo anti-angiogenesis effects resulting from lentivirus-mediated RNAi of vascular endothelial growth factor (VEGF) in monkeys with iris neovascularization (INV). METHODS: Five specific recombinant lentiviral vectors for RNA interference, targeting Macaca mulatta VEGFA, we...

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Detalles Bibliográficos
Autores principales: Yuan, Meng-Ke, Tao, Yong, Yu, Wen-Zhen, Kai, Wang, Jiang, Yan-Rong
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927369/
https://www.ncbi.nlm.nih.gov/pubmed/20806089