Cargando…
A Critical Analysis of Atoh7 (Math5) mRNA Splicing in the Developing Mouse Retina
The Math5 (Atoh7) gene is transiently expressed during retinogenesis by progenitors exiting mitosis, and is essential for ganglion cell (RGC) development. Math5 contains a single exon, and its 1.7 kb mRNA encodes a 149-aa polypeptide. Mouse Math5 mutants have essentially no RGCs or optic nerves. Giv...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927423/ https://www.ncbi.nlm.nih.gov/pubmed/20808762 http://dx.doi.org/10.1371/journal.pone.0012315 |