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A Critical Analysis of Atoh7 (Math5) mRNA Splicing in the Developing Mouse Retina

The Math5 (Atoh7) gene is transiently expressed during retinogenesis by progenitors exiting mitosis, and is essential for ganglion cell (RGC) development. Math5 contains a single exon, and its 1.7 kb mRNA encodes a 149-aa polypeptide. Mouse Math5 mutants have essentially no RGCs or optic nerves. Giv...

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Detalles Bibliográficos
Autores principales:	Prasov, Lev, Brown, Nadean L., Glaser, Tom
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927423/ https://www.ncbi.nlm.nih.gov/pubmed/20808762 http://dx.doi.org/10.1371/journal.pone.0012315

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