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GTPase regulator associated with the focal adhesion kinase (GRAF) transcript was down-regulated in patients with myeloid malignancies

BACKGROUND: GTPase regulator associated with the focal adhesion kinase (GRAF), a putative tumor suppressor gene, is found inactivated in hematopoietic malignancies by either genetic or epigenetic abnormalities. However, the expression level of GRAF gene has not yet been studied in leukemia. The aim...

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Detalles Bibliográficos
Autores principales: Qian, Zhen, Qian, Jun, Lin, Jiang, Yao, Dong-ming, Chen, Qin, Ji, Run-bi, Li, Yun, Xiao, Gao-fei, Li, Jian-yong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927506/
https://www.ncbi.nlm.nih.gov/pubmed/20704716
http://dx.doi.org/10.1186/1756-9966-29-111