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Production of glycoprotein vaccines in Escherichia coli

BACKGROUND: Conjugate vaccines in which polysaccharide antigens are covalently linked to carrier proteins belong to the most effective and safest vaccines against bacterial pathogens. State-of-the art production of conjugate vaccines using chemical methods is a laborious, multi-step process. In vivo...

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Detalles Bibliográficos
Autores principales: Ihssen, Julian, Kowarik, Michael, Dilettoso, Sandro, Tanner, Cyril, Wacker, Michael, Thöny-Meyer, Linda
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927510/
https://www.ncbi.nlm.nih.gov/pubmed/20701771
http://dx.doi.org/10.1186/1475-2859-9-61