TRIM5 Suppresses Cross-Species Transmission of a Primate Immunodeficiency Virus and Selects for Emergence of Resistant Variants in the New Species

Simian immunodeficiency viruses of sooty mangabeys (SIVsm) are the source of multiple, successful cross-species transmissions, having given rise to HIV-2 in humans, SIVmac in rhesus macaques, and SIVstm in stump-tailed macaques. Cellular assays and phylogenetic comparisons indirectly support a role...

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Detalles Bibliográficos
Autores principales: Kirmaier, Andrea, Wu, Fan, Newman, Ruchi M., Hall, Laura R., Morgan, Jennifer S., O'Connor, Shelby, Marx, Preston A., Meythaler, Mareike, Goldstein, Simoy, Buckler-White, Alicia, Kaur, Amitinder, Hirsch, Vanessa M., Johnson, Welkin E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927514/
https://www.ncbi.nlm.nih.gov/pubmed/20808775
http://dx.doi.org/10.1371/journal.pbio.1000462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927514/
https://www.ncbi.nlm.nih.gov/pubmed/20808775
http://dx.doi.org/10.1371/journal.pbio.1000462

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