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TRIM5 Suppresses Cross-Species Transmission of a Primate Immunodeficiency Virus and Selects for Emergence of Resistant Variants in the New Species
Simian immunodeficiency viruses of sooty mangabeys (SIVsm) are the source of multiple, successful cross-species transmissions, having given rise to HIV-2 in humans, SIVmac in rhesus macaques, and SIVstm in stump-tailed macaques. Cellular assays and phylogenetic comparisons indirectly support a role...
Autores principales: | Kirmaier, Andrea, Wu, Fan, Newman, Ruchi M., Hall, Laura R., Morgan, Jennifer S., O'Connor, Shelby, Marx, Preston A., Meythaler, Mareike, Goldstein, Simoy, Buckler-White, Alicia, Kaur, Amitinder, Hirsch, Vanessa M., Johnson, Welkin E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927514/ https://www.ncbi.nlm.nih.gov/pubmed/20808775 http://dx.doi.org/10.1371/journal.pbio.1000462 |
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