GFAP-Driven GFP Expression in Activated Mouse Müller Glial Cells Aligning Retinal Blood Vessels Following Intravitreal Injection of AAV2/6 Vectors

BACKGROUND: Müller cell gliosis occurs in various retinal pathologies regardless of the underlying cellular defect. Because activated Müller glial cells span the entire retina and align areas of injury, they are ideal targets for therapeutic strategies, including gene therapy. METHODOLOGY/PRINCIPAL...

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Detalles Bibliográficos
Autores principales: Aartsen, Wendy M., van Cleef, Koen W. R., Pellissier, Lucie P., Hoek, Robert M., Vos, Rogier M., Blits, Bas, Ehlert, Erich M. E., Balaggan, Kamaljit S., Ali, Robin R., Verhaagen, Joost, Wijnholds, Jan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927518/
https://www.ncbi.nlm.nih.gov/pubmed/20808778
http://dx.doi.org/10.1371/journal.pone.0012387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927518/
https://www.ncbi.nlm.nih.gov/pubmed/20808778
http://dx.doi.org/10.1371/journal.pone.0012387

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