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Immunogenic Profiling in Mice of a HIV/AIDS Vaccine Candidate (MVA-B) Expressing Four HIV-1 Antigens and Potentiation by Specific Gene Deletions

BACKGROUND: The immune parameters of HIV/AIDS vaccine candidates that might be relevant in protection against HIV-1 infection are still undefined. The highly attenuated poxvirus strain MVA is one of the most promising vectors to be use as HIV-1 vaccine. We have previously described a recombinant MVA...

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Detalles Bibliográficos
Autores principales: García-Arriaza, Juan, Nájera, José Luis, Gómez, Carmen E., Sorzano, Carlos Oscar S., Esteban, Mariano
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927552/
https://www.ncbi.nlm.nih.gov/pubmed/20811493
http://dx.doi.org/10.1371/journal.pone.0012395