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Mifepristone increases gamma-retroviral infection efficiency by enhancing integration of virus into the genome of infected cells

Gamma-retroviruses are commonly used to deliver genes to cells. Previously we demonstrated that the synthetic anti-glucocorticoid and anti-progestin agent, mifepristone, increased gamma-retroviral infection efficiency in different target cells, independent of viral titer. In this paper, we examine h...

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Detalles Bibliográficos
Autores principales: Solodushko, Victor, Fouty, Brian
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927725/
https://www.ncbi.nlm.nih.gov/pubmed/20485384
http://dx.doi.org/10.1038/gt.2010.80