Cargando…

Bicaudal-D Regulates Fragile X Mental Retardation Protein Levels, Motility, and Function during Neuronal Morphogenesis

The expression of the RNA-binding factor Fragile X mental retardation protein (FMRP) is disrupted in the most common inherited form of cognitive deficiency in humans. FMRP controls neuronal morphogenesis by mediating the translational regulation and localization of a large number of mRNA targets [1–...

Descripción completa

Detalles Bibliográficos
Autores principales: Bianco, Ambra, Dienstbier, Martin, Salter, Hannah K., Gatto, Graziana, Bullock, Simon L.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927779/
https://www.ncbi.nlm.nih.gov/pubmed/20691595
http://dx.doi.org/10.1016/j.cub.2010.07.016