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Bicaudal-D Regulates Fragile X Mental Retardation Protein Levels, Motility, and Function during Neuronal Morphogenesis
The expression of the RNA-binding factor Fragile X mental retardation protein (FMRP) is disrupted in the most common inherited form of cognitive deficiency in humans. FMRP controls neuronal morphogenesis by mediating the translational regulation and localization of a large number of mRNA targets [1–...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Cell Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927779/ https://www.ncbi.nlm.nih.gov/pubmed/20691595 http://dx.doi.org/10.1016/j.cub.2010.07.016 |