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Altered expression of glutamate signaling, growth factor and glia genes in the locus coeruleus of patients with major depression

Several studies have proposed that brain glutamate signaling abnormalities and glial pathology play a role in the etiology of major depressive disorder (MDD). These conclusions were primarily drawn from postmortem studies in which forebrain brain regions were examined. The locus coeruleus is the pri...

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Detalles Bibliográficos
Autores principales: Bernard, René, Kerman, Ilan A., Thompson, Robert C., Jones, Edward G., Bunney, William E., Barchas, Jack D., Schatzberg, Alan F., Myers, Richard M, Akil, Huda, Watson, Stanley J.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927798/
https://www.ncbi.nlm.nih.gov/pubmed/20386568
http://dx.doi.org/10.1038/mp.2010.44