Immune Cell–Derived C3 Is Required for Autoimmune Diabetes Induced by Multiple Low Doses of Streptozotocin

OBJECTIVE: The complement system contributes to autoimmune injury, but its involvement in promoting the development of autoimmune diabetes is unknown. In this study, our goal was to ascertain the role of complement C3 in autoimmune diabetes. RESEARCH DESIGN AND METHODS: Susceptibility to diabetes de...

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Detalles Bibliográficos
Autores principales: Lin, Marvin, Yin, Na, Murphy, Barbara, Medof, M. Edward, Segerer, Stephan, Heeger, Peter S., Schröppel, Bernd
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927947/
https://www.ncbi.nlm.nih.gov/pubmed/20584999
http://dx.doi.org/10.2337/db10-0044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927947/
https://www.ncbi.nlm.nih.gov/pubmed/20584999
http://dx.doi.org/10.2337/db10-0044

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