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Immune Cell–Derived C3 Is Required for Autoimmune Diabetes Induced by Multiple Low Doses of Streptozotocin
OBJECTIVE: The complement system contributes to autoimmune injury, but its involvement in promoting the development of autoimmune diabetes is unknown. In this study, our goal was to ascertain the role of complement C3 in autoimmune diabetes. RESEARCH DESIGN AND METHODS: Susceptibility to diabetes de...
Autores principales: | Lin, Marvin, Yin, Na, Murphy, Barbara, Medof, M. Edward, Segerer, Stephan, Heeger, Peter S., Schröppel, Bernd |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927947/ https://www.ncbi.nlm.nih.gov/pubmed/20584999 http://dx.doi.org/10.2337/db10-0044 |
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