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Variation in the ATP-binding cassette transporter 2 gene is a separate risk factor for Systemic Lupus Erythematosus within the MHC

The ATP-binding cassette transporter (TAP) proteins are functionally relevant candidates for predisposition to Systemic Lupus Erythematosus (SLE) by virtue of their role in autoantigen presentation and location in the MHC. We tested if variation in the TAP genes (TAP1 and TAP2) is associated with SL...

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Detalles Bibliográficos
Autores principales: Ramos, Paula S., Langefeld, Carl D., Bera, LeeAnn, Gaffney, Patrick M., Noble, Janelle A., Moser, Kathy L.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927958/
https://www.ncbi.nlm.nih.gov/pubmed/19387463
http://dx.doi.org/10.1038/gene.2009.21