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SMAD4 - Molecular gladiator of the TGF-β signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRAS proto-oncogene

BACKGROUND: The development and progression of colorectal cancer has been extensively studied and the genes responsible have been well characterized. However the correlation between the SMAD4 gene mutations with KRAS mutant status has not been explored by many studies so far. Here, in this study we...

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Detalles Bibliográficos
Autores principales: Sameer, A Syed, Chowdri, Nissar A, Syeed, Nidda, Banday, Mujeeb Z, Shah, Zaffar A, Siddiqi, Mushtaq A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927996/
https://www.ncbi.nlm.nih.gov/pubmed/20565773
http://dx.doi.org/10.1186/1471-2407-10-300