Promoter methylation of CDKN2A and lack of p16 expression characterize patients with hepatocellular carcinoma

BACKGROUND: The product of CDKN2A, p16 is an essential regulator of the cell cycle controlling the entry into the S-phase. Herein, we evaluated CDKN2A promoter methylation and p16 protein expression for the differentiation of hepatocellular carcinoma (HCC) from other liver tumors. METHODS: Tumor and...

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Detalles Bibliográficos
Autores principales: Csepregi, Antal, Ebert, Matthias PA, Röcken, Christoph, Schneider-Stock, Regine, Hoffmann, Juliane, Schulz, Hans-Ulrich, Roessner, Albert, Malfertheiner, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927998/
https://www.ncbi.nlm.nih.gov/pubmed/20569442
http://dx.doi.org/10.1186/1471-2407-10-317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927998/
https://www.ncbi.nlm.nih.gov/pubmed/20569442
http://dx.doi.org/10.1186/1471-2407-10-317

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