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Oxidative status of muscle is determined by p107 regulation of PGC-1α

Mice lacking p107 exhibit a white adipose deficiency yet do not manifest the metabolic changes typical for lipodystrophy, and instead exhibit low levels of serum triglycerides and a normal liver phenotype. When fed a high fat diet, p107-null mice still did not accumulate fat in the liver, and displa...

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Detalles Bibliográficos
Autores principales: Scimè, Anthony, Soleimani, Vahab D., Bentzinger, C. Florian, Gillespie, Mark A., Le Grand, Fabien, Grenier, Guillaume, Bevilacqua, Lisa, Harper, Mary-Ellen, Rudnicki, Michael A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928004/
https://www.ncbi.nlm.nih.gov/pubmed/20713602
http://dx.doi.org/10.1083/jcb.201005076