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Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration

Transendothelial migration (TEM) is a tightly regulated process whereby leukocytes migrate from the vasculature into tissues. Rho guanosine triphosphatases (GTPases) are implicated in TEM, but the contributions of individual Rho family members are not known. In this study, we use an RNA interference...

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Detalles Bibliográficos
Autores principales: Heasman, Sarah J., Carlin, Leo M., Cox, Susan, Ng, Tony, Ridley, Anne J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928012/
https://www.ncbi.nlm.nih.gov/pubmed/20733052
http://dx.doi.org/10.1083/jcb.201002067