Cargando…

Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression

BACKGROUND: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a complex network that regulate the state of chromatin and processes that depend on it including transcription and DNA replicatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Xiaojiang, Hoang, Stephen, Mayo, Marty W, Bekiranov, Stefan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928206/
https://www.ncbi.nlm.nih.gov/pubmed/20653935
http://dx.doi.org/10.1186/1471-2105-11-396