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Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression

BACKGROUND: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a complex network that regulate the state of chromatin and processes that depend on it including transcription and DNA replicatio...

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Detalles Bibliográficos
Autores principales:	Xu, Xiaojiang, Hoang, Stephen, Mayo, Marty W, Bekiranov, Stefan
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928206/ https://www.ncbi.nlm.nih.gov/pubmed/20653935 http://dx.doi.org/10.1186/1471-2105-11-396

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