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Homologous illegitimate random integration of foreign DNA into the X chromosome of a transgenic mouse line

BACKGROUND: It is not clear how foreign DNA molecules insert into the host genome. Recently, we have produced transgenic mice to investigate the role of the fad2 gene in the conversion of oleic acid to linoleic acid. Here we describe an integration mechanism of fad2 transgene by homologous illegitim...

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Detalles Bibliográficos
Autores principales: Yan, Bowen, Li, Defa, Gou, Kemian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928235/
https://www.ncbi.nlm.nih.gov/pubmed/20707910
http://dx.doi.org/10.1186/1471-2199-11-58