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Homologous illegitimate random integration of foreign DNA into the X chromosome of a transgenic mouse line
BACKGROUND: It is not clear how foreign DNA molecules insert into the host genome. Recently, we have produced transgenic mice to investigate the role of the fad2 gene in the conversion of oleic acid to linoleic acid. Here we describe an integration mechanism of fad2 transgene by homologous illegitim...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928235/ https://www.ncbi.nlm.nih.gov/pubmed/20707910 http://dx.doi.org/10.1186/1471-2199-11-58 |