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PPARα Is Essential for Microparticle-Induced Differentiation of Mouse Bone Marrow-Derived Endothelial Progenitor Cells and Angiogenesis

BACKGROUND: Bone marrow-derived endothelial progenitor cells (EPCs) are critical for neovascularization. We hypothesized that microparticles (MPs), small fragments generated from the plasma membrane, can activate angiogenic programming of EPCs. METHODOLOGY/PRINCIPAL FINDINGS: We studied the effects...

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Detalles Bibliográficos
Autores principales: Benameur, Tarek, Tual-Chalot, Simon, Andriantsitohaina, Ramaroson, Martínez, María Carmen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928272/
https://www.ncbi.nlm.nih.gov/pubmed/20811625
http://dx.doi.org/10.1371/journal.pone.0012392