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Modeling Core Metabolism in Cancer Cells: Surveying the Topology Underlying the Warburg Effect

BACKGROUND: Alterations on glucose consumption and biosynthetic activity of amino acids, lipids and nucleotides are metabolic changes for sustaining cell proliferation in cancer cells. Irrevocable evidence of this fact is the Warburg effect which establishes that cancer cells prefers glycolysis over...

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Detalles Bibliográficos
Autores principales: Resendis-Antonio, Osbaldo, Checa, Alberto, Encarnación, Sergio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928278/
https://www.ncbi.nlm.nih.gov/pubmed/20811631
http://dx.doi.org/10.1371/journal.pone.0012383