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Chromosome Tips Damaged in Anaphase Inhibit Cytokinesis

Genome maintenance is ensured by a variety of biochemical sensors and pathways that repair accumulated damage. During mitosis, the mechanisms that sense and resolve DNA damage remain elusive. Studies have demonstrated that damage accumulated on lagging chromosomes can activate the spindle assembly c...

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Detalles Bibliográficos
Autores principales: Baker, Norman M., Zeitlin, Samantha G., Shi, Linda Z., Shah, Jagesh, Berns, Michael W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928297/
https://www.ncbi.nlm.nih.gov/pubmed/20811641
http://dx.doi.org/10.1371/journal.pone.0012398