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The RhoA GEF Syx Is a Target of Rnd3 and Regulated via a Raf1-Like Ubiquitin-Related Domain

BACKGROUND: Rnd3 (RhoE) protein belongs to the unique branch of Rho family GTPases that has low intrinsic GTPase activity and consequently remains constitutively active [1], [2]. The current consensus is that Rnd1 and Rnd3 function as important antagonists of RhoA signaling primarily by activating t...

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Detalles Bibliográficos
Autores principales: Goh, Liuh Ling, Manser, Ed
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928299/
https://www.ncbi.nlm.nih.gov/pubmed/20811643
http://dx.doi.org/10.1371/journal.pone.0012409