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Characterization of Botulinum Neurotoxin Type A Neutralizing Monoclonal Antibodies and Influence of Their Half-Lives on Therapeutic Activity

Botulinum toxins, i.e. BoNT/A to/G, include the most toxic substances known. Since botulism is a potentially fatal neuroparalytic disease with possible use as a biowarfare weapon (Centers for Disease Control and Prevention category A bioterrorism agent), intensive efforts are being made to develop v...

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Detalles Bibliográficos
Autores principales: Mazuet, Christelle, Dano, Julie, Popoff, Michel R., Créminon, Christophe, Volland, Hervé
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928723/
https://www.ncbi.nlm.nih.gov/pubmed/20865035
http://dx.doi.org/10.1371/journal.pone.0012416