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Bayesian Linkage Analysis of Categorical Traits for Arbitrary Pedigree Designs

BACKGROUND: Pedigree studies of complex heritable diseases often feature nominal or ordinal phenotypic measurements and missing genetic marker or phenotype data. METHODOLOGY: We have developed a Bayesian method for Linkage analysis of Ordinal and Categorical traits (LOCate) that can analyze complex...

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Detalles Bibliográficos
Autores principales: Brisbin, Abra, Weissman, Myrna M., Fyer, Abby J., Hamilton, Steven P., Knowles, James A., Bustamante, Carlos D., Mezey, Jason G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928726/
https://www.ncbi.nlm.nih.gov/pubmed/20865038
http://dx.doi.org/10.1371/journal.pone.0012307