Computational Prediction and Experimental Verification of New MAP Kinase Docking Sites and Substrates Including Gli Transcription Factors

In order to fully understand protein kinase networks, new methods are needed to identify regulators and substrates of kinases, especially for weakly expressed proteins. Here we have developed a hybrid computational search algorithm that combines machine learning and expert knowledge to identify kina...

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Detalles Bibliográficos
Autores principales: Whisenant, Thomas C., Ho, David T., Benz, Ryan W., Rogers, Jeffrey S., Kaake, Robyn M., Gordon, Elizabeth A., Huang, Lan, Baldi, Pierre, Bardwell, Lee
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928751/
https://www.ncbi.nlm.nih.gov/pubmed/20865152
http://dx.doi.org/10.1371/journal.pcbi.1000908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928751/
https://www.ncbi.nlm.nih.gov/pubmed/20865152
http://dx.doi.org/10.1371/journal.pcbi.1000908

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