Disruption of the Lipid-Transporting LdMT-LdRos3 Complex in Leishmania donovani Affects Membrane Lipid Asymmetry but Not Host Cell Invasion

Maintenance and regulation of the asymmetric lipid distribution across eukaryotic plasma membranes is governed by the concerted action of specific membrane proteins controlling lipid movement across the bilayer. Here, we show that the miltefosine transporter (LdMT), a member of the P4-ATPase subfami...

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Detalles Bibliográficos
Autores principales: Weingärtner, Adrien, Drobot, Björn, Herrmann, Andreas, Sánchez-Cañete, María P., Gamarro, Francisco, Castanys, Santiago, Günther Pomorski, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928753/
https://www.ncbi.nlm.nih.gov/pubmed/20865154
http://dx.doi.org/10.1371/journal.pone.0012443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928753/
https://www.ncbi.nlm.nih.gov/pubmed/20865154
http://dx.doi.org/10.1371/journal.pone.0012443

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