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A kinetic model of TBP auto-regulation exhibits bistability

BACKGROUND: TATA Binding Protein (TBP) is required for transcription initiation by all three eukaryotic RNA polymerases. It participates in transcriptional initiation at the majority of eukaryotic gene promoters, either by direct association to the TATA box upstream of the transcription start site o...

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Detalles Bibliográficos
Autores principales: Gokhale, Sucheta A, Roshan, Reema, Khetan, Vivek, Pillai, Beena, Gadgil, Chetan J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928763/
https://www.ncbi.nlm.nih.gov/pubmed/20687914
http://dx.doi.org/10.1186/1745-6150-5-50