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Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells

BACKGROUND: Fatal neurodegenerative disorders such as Creutzfeldt-Jakob and Gerstmann-Sträussler-Scheinker diseases in humans, scrapie and bovine spongiform encephalopathy in animals, are characterized by the accumulation in the brain of a pathological form of the prion protein (PrP) denominated PrP...

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Detalles Bibliográficos
Autores principales: Didonna, Alessandro, Legname, Giuseppe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928767/
https://www.ncbi.nlm.nih.gov/pubmed/20696038
http://dx.doi.org/10.1186/1750-1326-5-29