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A Phenomenological Model for Predicting Melting Temperatures of DNA Sequences
We report here a novel method for predicting melting temperatures of DNA sequences based on a molecular-level hypothesis on the phenomena underlying the thermal denaturation of DNA. The model presented here attempts to quantify the energetic components stabilizing the structure of DNA such as base p...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928768/ https://www.ncbi.nlm.nih.gov/pubmed/20865157 http://dx.doi.org/10.1371/journal.pone.0012433 |