Cargando…

Evidence of Functional Protein Dynamics from X-Ray Crystallographic Ensembles

It is widely recognized that representing a protein as a single static conformation is inadequate to describe the dynamics essential to the performance of its biological function. We contrast the amino acid displacements below and above the protein dynamical transition temperature, T(D)∼215K, of hen...

Descripción completa

Detalles Bibliográficos
Autores principales: Kohn, Jonathan E., Afonine, Pavel V., Ruscio, Jory Z., Adams, Paul D., Head-Gordon, Teresa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928775/
https://www.ncbi.nlm.nih.gov/pubmed/20865158
http://dx.doi.org/10.1371/journal.pcbi.1000911