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Linking Changes in Epithelial Morphogenesis to Cancer Mutations Using Computational Modeling

Most tumors arise from epithelial tissues, such as mammary glands and lobules, and their initiation is associated with the disruption of a finely defined epithelial architecture. Progression from intraductal to invasive tumors is related to genetic mutations that occur at a subcellular level but man...

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Detalles Bibliográficos
Autores principales: Rejniak, Katarzyna A., Wang, Shizhen E., Bryce, Nicole S., Chang, Hang, Parvin, Bahram, Jourquin, Jerome, Estrada, Lourdes, Gray, Joe W., Arteaga, Carlos L., Weaver, Alissa M., Quaranta, Vito, Anderson, Alexander R. A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928778/
https://www.ncbi.nlm.nih.gov/pubmed/20865159
http://dx.doi.org/10.1371/journal.pcbi.1000900