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Linking Changes in Epithelial Morphogenesis to Cancer Mutations Using Computational Modeling
Most tumors arise from epithelial tissues, such as mammary glands and lobules, and their initiation is associated with the disruption of a finely defined epithelial architecture. Progression from intraductal to invasive tumors is related to genetic mutations that occur at a subcellular level but man...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928778/ https://www.ncbi.nlm.nih.gov/pubmed/20865159 http://dx.doi.org/10.1371/journal.pcbi.1000900 |