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Extracellular Dopamine Potentiates Mn-Induced Oxidative Stress, Lifespan Reduction, and Dopaminergic Neurodegeneration in a BLI-3–Dependent Manner in Caenorhabditis elegans

Parkinson's disease (PD)-mimicking drugs and pesticides, and more recently PD-associated gene mutations, have been studied in cell cultures and mammalian models to decipher the molecular basis of PD. Thus far, a dozen of genes have been identified that are responsible for inherited PD. However...

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Detalles Bibliográficos
Autores principales: Benedetto, Alexandre, Au, Catherine, Avila, Daiana Silva, Milatovic, Dejan, Aschner, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928785/
https://www.ncbi.nlm.nih.gov/pubmed/20865164
http://dx.doi.org/10.1371/journal.pgen.1001084