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Extracellular Dopamine Potentiates Mn-Induced Oxidative Stress, Lifespan Reduction, and Dopaminergic Neurodegeneration in a BLI-3–Dependent Manner in Caenorhabditis elegans
Parkinson's disease (PD)-mimicking drugs and pesticides, and more recently PD-associated gene mutations, have been studied in cell cultures and mammalian models to decipher the molecular basis of PD. Thus far, a dozen of genes have been identified that are responsible for inherited PD. However...
Autores principales: | Benedetto, Alexandre, Au, Catherine, Avila, Daiana Silva, Milatovic, Dejan, Aschner, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928785/ https://www.ncbi.nlm.nih.gov/pubmed/20865164 http://dx.doi.org/10.1371/journal.pgen.1001084 |
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