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Distinct Merkel Cell Polyomavirus Molecular Features in Tumour and Non Tumour Specimens from Patients with Merkel Cell Carcinoma

Merkel Cell Polyomavirus (MCPyV) is associated with Merkel Cell carcinoma (MCC), a rare, aggressive skin cancer with neuroendocrine features. The causal role of MCPyV is highly suggested by monoclonal integration of its genome and expression of the viral large T (LT) antigen in MCC cells. We investi...

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Detalles Bibliográficos
Autores principales: Laude, Hélène C., Jonchère, Barbara, Maubec, Eve, Carlotti, Agnès, Marinho, Eduardo, Couturaud, Benoit, Peter, Martine, Sastre-Garau, Xavier, Avril, Marie-Françoise, Dupin, Nicolas, Rozenberg, Flore
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928786/
https://www.ncbi.nlm.nih.gov/pubmed/20865165
http://dx.doi.org/10.1371/journal.ppat.1001076