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Direct Interaction between Two Viral Proteins, the Nonstructural Protein 2C(ATPase) and the Capsid Protein VP3, Is Required for Enterovirus Morphogenesis

In spite of decades-long studies, the mechanism of morphogenesis of plus-stranded RNA viruses belonging to the genus Enterovirus of Picornaviridae, including poliovirus (PV), is not understood. Numerous attempts to identify an RNA encapsidation signal have failed. Genetic studies, however, have impl...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Wang, Chunling, Mueller, Steffen, Paul, Aniko V., Wimmer, Eckard, Jiang, Ping
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928791/
https://www.ncbi.nlm.nih.gov/pubmed/20865167
http://dx.doi.org/10.1371/journal.ppat.1001066