Human Sulfatase 2 inhibits in vivo tumor growth of MDA-MB-231 human breast cancer xenografts

BACKGROUND: Extracellular human sulfatases modulate growth factor signaling by alteration of the heparin/heparan sulfate proteoglycan (HSPG) 6-O-sulfation state. HSPGs bind to numerous growth factor ligands including fibroblast growth factors (FGF), epidermal growth factors (EGF), and vascular endot...

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Detalles Bibliográficos
Autores principales: Peterson, Sarah M, Iskenderian, Andrea, Cook, Lynette, Romashko, Alla, Tobin, Kristen, Jones, Michael, Norton, Angela, Gómez-Yafal, Alicia, Heartlein, Michael W, Concino, Michael F, Liaw, Lucy, Martini, Paolo GV
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928797/
https://www.ncbi.nlm.nih.gov/pubmed/20707913
http://dx.doi.org/10.1186/1471-2407-10-427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928797/
https://www.ncbi.nlm.nih.gov/pubmed/20707913
http://dx.doi.org/10.1186/1471-2407-10-427

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